All episodes

The Role of Oncology Nurses and Advanced Practice Providers in the Treatment of Patients With HRR-Deficient mCRPC Receiving Talazoparib Plus Enzalutamide: A Podcast

This podcast is published open access in Oncology and Therapy and is fully citeable. You can access the original published podcast article through the Oncology and Therapy website and by using this link: https://link.springer.com/article/10.1007/s40487-025-00376-w. All conflicts of interest can be found online. This podcast is intended for medical professionals.

Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or...

Managing Drug Interactions with Enzalutamide in Patients with Prostate Cancer

This podcast is published open access in Drug Safety and is fully citeable. You can access the original published podcast article through the Drug Safety website and by using this link: https://link.springer.com/article/10.1007/s40264-025-01600-2.

All conflicts of interest can be found online. This podcast is intended for medical professionals.

Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source,...

From Non-believer to Believer: A Podcast Conversation on the Journey from Skeptic to Proponent of Oncology Real-World Evidence

In this podcast, the hosts Dr Adam Brufsky and Dr Raymond Liu share their personal experiences with real-world evidence (RWE) and how they have come to be advocates for considering RWE as a supplement to randomized controlled trial (RCT) findings to help guide decision making in the clinic. They discuss the limitations of RCTs in capturing diverse patient populations and highlight the value of RWE in providing insights into underrepresented groups, such as patients with high Eastern Cooperative Oncology Group (ECOG) performance...

A Practical Approach to Understanding Real-World Study Methodology in Cancer Research: A Vodcast

This vodcast intends to be a practical guide for clinicians by clarifying aspects of real-world study methodology. As both practicing oncologists and researchers with extensive real-world data experience, the hosts Dr Adam Brufsky and Dr Winson Cheung discuss types of study designs and real-world data source considerations. An overview of statistical techniques for mitigating treatment-selection bias is also provided, including propensity score matching, inverse probability of treatment weighting, and multivariable analysis. By combining high-quality data sources, careful sample size considerations, and rigorous statistical techniques, real-world studies can...

Real-World Studies and Randomized Controlled Trials: A Podcast Discussion of the Relative Strengths and Limitations of These Complementary Designs for Cancer Research

This podcast aims to be a resource for clinicians by exploring the strengths and limitations of randomized controlled trials (RCTs) and real-world studies in the context of cancer research. The hosts Dr Adam Brufsky and Dr Christos Vaklavas, both of whom are practicing oncologists, provide context for the emergence of modern real-world studies and advice for interpreting real-world evidence. As a supplement to learnings from RCTs, real-world evidence can inform the treatment decision-making process in the clinic and...

In this podcast "Treatment Optimization and Management of AEs with Enfortumab Vedotin + Pembrolizumab for Untreated Locally Advanced/Metastatic Urothelial Cancer: A Podcast", authors discuss the management of adverse events (AEs) with enfortumab vedotin + pembrolizumab based on their personal experiences with clinical trials and in their practices and provide perspectives for healthcare professionals on practical management of common AEs and effective dose management strategies. This may help improve the patient experience and allow patients to stay on therapy for longer, leading to optimized treatment outcomes.

This podcast is published open access in Oncology and Therapy and is fully citeable. You can access the original...

In this podcast, Dr. Zoe Apalla from the Aristotle University of Thessaloniki, Thessaloniki, Greece, and Dr. Katya Harfmann from the Nationwide Children’s Hospital, Columbus, OH, USA discuss tools for assessing alopecia areata severity, including the Severity of Alopecia Tool, AA Scale, and AA Severity and Morbidity Index. An interactive digital feature is provided for this article at the following link: https://datahub.pfizer.com/aaseverity.

This podcast is published open access in the American Journal of Clinical Dermatology and is fully citeable. You can access the original published vodcast article through the American Journal of Clinical Dermatology website and by using this link: https://link.springer.com/article/10.1007/s40257-025-00973-5....

This podcast is published open access in Dermatology and Therapy and is fully citeable. You can access the original published podcast article through the Dermatology and Therapy website and by using this link: https://link.springer.com/article/10.1007/s13555-025-01491-2. All conflicts of interest can be found online. This podcast is intended for medical professionals.

Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence,...

Avelumab first-line maintenance is an approved treatment for cisplatin-eligible or -ineligible patients with advanced urothelial carcinoma (UC) who are progression free following first-line platinum-based chemotherapy, based on the results of the JAVELIN Bladder 100 phase 3 trial. In recent years, an increasing number of real-world studies have examined the effectiveness and safety of avelumab first-line maintenance in heterogeneous populations from different countries, expanding the clinical evidence base. In this podcast, Dr. Petros Grivas from the University of Washington, Fred Hutch Cancer Center, Seattle, WA, USA, and Dr. Helen H. Moon from Kaiser Permanente, Riverside, CA, USA, discuss findings from these...

In this podcast, Dr. Brittany M. Szymaniak from the Feinberg School of Medicine at Northwestern University, Chicago, IL, USA, Dr. Alicia K. Morgans from the Dana-Farber Cancer Institute, Boston, MA, USA, and Dr. Neal D. Shore from the Carolina Urologic Research Center, Myrtle Beach, SC, USA, aim to identify obstacles to testing for homologous recombination repair (HRR) gene alterations in patients with prostate cancer that healthcare professionals encounter in day-to-day clinical practice, as well as discuss ways to potentially overcome them. This podcast is published open access in Targeted Oncology and is fully citeable. You can access the original published...